Abstract Metabolic syndrome (MeS) is a common multifaceted disorder.Plants contain antioxidant bioactive compounds, which are beneficial to improve the health condition of patients with MeS.Propolis is a hive natural product that is composed of various constituent.We aimed to assess the effects of Iranian propolis as a natural and safe Axle agent on indicators of MeS, quality of life and mood status in individuals with MeS.
In total, 66 interested eligible patients recruited to the present study.Participants were randomly assigned to consume a tablet at dose of 250 mg of propolis extract, twice daily for 12 weeks or placebo.Propolis supplementation could lead to a significant reduction in waist circumference (WC), Washers increase in physical functioning, general health and the overall score of SF-36 compared with placebo group (P-value 0.05).
The current study indicated that propolis can be effective in decreasing WC and improving physical health and quality of life, while had no significant effects on other components of MeS among subjects with this syndrome.Clinical trials registration Iran Registry of Clinical Trials.ir IRCT20121216011763N49, registration date 23/12/2020.